Assessment & management Definition A non-fasting triglyceride level above the normal range (>2 mmol/L) – repeat with patient fasted to confirm the diagnosis. Assessment Exclude secondary causes: Alcohol excessObesityDiabetesDrugs causes (e.g. steroid hormones)HypothyroidismFatty liver disease of any cause Management Fasting triglyceride level (mmol/L)Action4.5-9.9Lifestyle interventions to reduce cardiovascular risk. No specific drug treatment is indicated>10Seek specialist advice – patient is at risk of pancreatitisConsider starting a fibrate Be aware that risk assessment tools will underestimate the CVD risk This article was published on 2025-05-21