Adherence Testing

In some cases it may be useful to check for adherence to the existing drug regimen, particularly when there has been no apparent response to 3 or more drugs.

This investigation should only be requested after: 

  • Persisting hypertension is confirmed by ABPM.
  • The patient is on a 4-drug regimen, (including at least 1 diuretic). 

 

Adherence testing is arranged through the cardiovascular risk clinic via SCI gateway referral as per guidance on Refhelp.

 

List of drugs that can be tested for: 

 

ACE inhibitorEnalapril, Lisinopril, Perindopril, Quinapril, Ramipril, Trandolapril
Angiotensin-Receptor blockersCandesartan, Irbesartan, Losartan, Olmesartan, Valsartan
Calcium channel blockersAmlodipine, Diltiazem, Felodipine, Lacidipine, Lercanidipine, Nifedipine, Verapamil
Diuretics

Thiazide/thiazide-like: Bendroflumethiazide, Chlortalidone, Hydrochlorothiazide, Indapamide

K+-sparing: Amiloride, Eplerenone, Spironolactone

Loop: Furosemide, Bumetanide

Beta-adrenoceptor blockersAtenolol, Bisoprolol, Labetalol, Metoprolol
Alpha-adrenoceptor blockersDoxazosin
Centrally-acting drugsMethyldopa, Minoxidil, Moxonidine
OtherAliskiren, Hydralazine

 

 

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